# Is it safe to skip high dose chemotherapy and BMT

**URL:** <https://nbforum.discourse.group/t/is-it-safe-to-skip-high-dose-chemotherapy-and-bmt/533>\
**Category:** Treatment / Research\
**Created:** [April 5, 2018, 10:02am UTC](https://nbforum.discourse.group/t/is-it-safe-to-skip-high-dose-chemotherapy-and-bmt/533 "2018-04-05T10:02:44Z")\
**Posts on this page:** 1\
**Showing post:** 14

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**Author:** ![sam](https://sea1.discourse-cdn.com/flex019/user_avatar/nbforum.discourse.group/sam/32/12_2.png) [@sam](https://nbforum.discourse.group/u/sam)\
**Post date:** [September 16, 2019, 8:10am UTC](https://nbforum.discourse.group/t/is-it-safe-to-skip-high-dose-chemotherapy-and-bmt/533/14 "2019-09-16T08:10:07Z")

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I wrote a bit about clinical trials here: [How do you pick which clinical trials to join?](https://nbforum.discourse.group/t/how-do-you-pick-which-clinical-trials-to-join/259)

hu3F8 is still just in Phase 2. So we know what dosages we can give, and we can measure there is a lot of antibody in the blood. But… it is going to take another 5 years until long term studies are published.

MSK have graphs that they share yearly and the graphs they share comparing 3F8 to hu3F8 always show a marked improvement when they introduced hu3F8.

ch14.18 is quite an intense experience, involving a week plus of hospitalization (for standard non long term infusion). hu3F8 in comparison is a day visit to the hospital and a 1 hour infusion after which you go home.

The big ray of light here is that an international trial is in progress: [Naxitamab for High-Risk Neuroblastoma Patients With Primary Refractory Disease or Incomplete Response to Salvage Treatment in Bone and/or Bone Marrow - Full Text View - ClinicalTrials.gov](https://clinicaltrials.gov/ct2/show/NCT03363373)

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